July 22, 2019Open Access
Clinical Effectiveness of Direct Oral Anticoagulants vs Warfarin in Older Patients With Atrial Fibrillation and Ischemic Stroke
Structured PICO
Does DOAC use at discharge improve long-term outcomes in older patients with acute ischemic stroke and atrial fibrillation compared to warfarin?
P
Population
Older patients with acute ischemic stroke and atrial fibrillation (AF)
I
Intervention
Direct oral anticoagulants (DOACs) at discharge
C
Comparator
Warfarin
O
Outcome
Long-term outcomes
In older patients with atrial fibrillation and acute ischemic stroke, discharging on a DOAC rather than warfarin is associated with better long-term outcomes.
Abstract
In patients with acute ischemic stroke and AF, DOAC use at discharge was associated with better long-term outcomes relative to warfarin.