Why the study?
Does arterial occlusion increase the responsiveness of group III and IV afferents to dynamic exercise in decerebrate cats?
Population
Decerebrate unanesthetized cats
Comparison
Arterial occlusion to dynamically exercising… vs Freely perfused state
Design
Preclinical
Authors
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Extends mechanistic insight into ischemic afferent sensitization; leaves open metabolite identity and human translation.
Does arterial occlusion increase the responsiveness of group III and IV afferents to dynamic exercise in decerebrate cats?
Arterial occlusion during dynamic exercise increases the sensitivity of group III and IV muscle afferents via an unspecified accumulating substance, independent of hydrogen or lactate ions.
Adreani et al. (1998) studied this question.
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