Why the study?
Does inhibition of ROCK and MEK reduce cell migration and proliferation in human glioblastoma cells?
Does inhibition of ROCK and MEK reduce cell migration and proliferation in human glioblastoma cells?
Rho/ROCK signaling is involved in glioblastoma cell migration and proliferation, and its combined inhibition with the MAPK pathway provides greater suppression of these processes in vitro.
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Brown et al. (2006) studied this question.
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