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May 29, 2019New England Journal of Medicine1,016 citationsOpen Access

Daratumumab plus Lenalidomide and Dexamethasone for Untreated Myeloma

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Thierry Façon
Thierry FaçonRoswell Park Comprehensive Cancer Center
Shaji Kumar
Shaji KumarMayo Clinic
TPTorben PlesnerUniversity of Southern Denmark

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Abstract

Among patients with newly diagnosed multiple myeloma who were ineligible for autologous stem-cell transplantation, the risk of disease progression or death was significantly lower among those who received daratumumab plus lenalidomide and dexamethasone than among those who received lenalidomide and dexamethasone alone. A higher incidence of neutropenia and pneumonia was observed in the daratumumab group. (Funded by Janssen Research and Development; MAIA ClinicalTrials.gov number, NCT02252172.).

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Cite This Study

Façon et al. (2019) studied this question.

synapsesocial.com/papers/69dbc19bc9a120f055a3c6ebhttps://doi.org/10.1056/nejmoa1817249
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