November 25, 2015Open Access

Systematic review with meta‐analysis: mucosal healing is associated with improved long‐term outcomes in Crohn's disease

SSShailja C. ShahSan Francisco VA Medical Center

Jean‐Frédéric ColombelSemmelweis University

Bruce E. SandsStatens Serum Institut

Key Points

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Abstract

Achieving MH1 is associated with increased rates of long-term clinical remission, and maintenance of mucosal healing in active Crohn's disease and may therefore be a reasonable therapeutic target.

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Shah et al. (Wed,) studied this question.

synapsesocial.com/papers/69dbc7677d378569a9835b70 https://doi.org/https://doi.org/10.1111/apt.13475

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3Oral budesonide as maintenance treatment for Crohn's disease: A placebo-controlled, dose-ranging study. Canadian Inflammatory Bowel Disease Study Group1996 · 293 citations
4Impact of Elemental Diet on Mucosal Inflammation in Patients with Active Crohnʼs Disease: Cytokine Production and Endoscopic and Histological Findings2005 · 181 citations
5Mucosal Healing in Crohnʼs Disease2012 · 141 citations

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