Why the study?
Are elevated levels of remnant lipoproteins associated with plasma platelet microparticles in patients with type-2 diabetes mellitus without obstructive coronary artery disease?
Population
Patients with type-2 diabetes mellitus without obstructive coronary artery disease, and controls
Design
Case-control
Authors
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Supports remnant lipoproteins as driver of platelet microparticles in T2DM; hypothesis-generating, should not yet change practice.
Are elevated levels of remnant lipoproteins associated with plasma platelet microparticles in patients with type-2 diabetes mellitus without obstructive coronary artery disease?
Elevated RLP-cholesterol is an independent predictor of platelet microparticles in type-2 diabetes, suggesting a potential target for lipid-lowering therapy to prevent thrombogenic complications.
Koga et al. (2006) studied this question.
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