March 27, 2020JAMA CardiologyOpen Access

Cardiac Involvement in a Patient With Coronavirus Disease 2019 (COVID-19)

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Why the study?

Although viral infection is a common cause of myocarditis, less was known about cardiac involvement as a complication of SARS-CoV-2 infection.

Design

Case report

Authors

RIRiccardo M. InciardiHeart Failure / Cardiomyopathy LLLaura LupiSurgical Specialties (Canada)GZG ZacconeMaria Eleonora Hospital

Discussion

Member takes

Implication

Myopericarditis without pneumonia may occur in COVID-19; hypothesis-generating for direct cardiotropism and requires prospective validation.

Structured PICO

Population

An otherwise healthy 53-year-old white woman who tested positive for COVID-19 and developed acute myopericarditis with systolic dysfunction.

Intervention

Treatment with dobutamine, antiviral drugs (lopinavir/ritonavir), steroids, chloroquine, and medical treatment for heart failure.

Outcome

Detection of cardiac involvement with an increase in levels of NT-proBNP and high-sensitivity troponin T, echocardiography changes, and diffuse biventricular myocardial edema and late gadolinium enhancement on cardiac magnetic resonance imaging.surrogate

This case highlights that COVID-19 can cause acute myopericarditis and severe left ventricular dysfunction even in the absence of interstitial pneumonia.

Cite This Study

Inciardi et al. (2020) studied this question.

synapsesocial.com/papers/69dbcc385b363cdf1c835f3c https://doi.org/10.1001/jamacardio.2020.1096

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Implication

Myopericarditis without pneumonia may occur in COVID-19; hypothesis-generating for direct cardiotropism and requires prospective validation.