In vitro investigation demonstrates strong antibiotic synergy for zinc-based nanoparticles against broad-spectrum bacterial pathogens, suggesting improved treatment options for severe infections.
Pathogen bacteria strains with wide spectrum can cause serious infections with drastic damages on humans. There are studies reflecting antibacterial effect of nanoparticles type metal or metal oxides as an alternative or concurrent treatment to the diseases caused by infectious agents. Synthesised nanoparticles using different methods like sol-gel, hydrothermal or plant extraction were tested following well-established protocols with the regard to their antimicrobial activity. It was found that zinc based nanoparticles possess strong synergistic effect with commonly used antibiotics on infection tratment.
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Chiriac et al. (2016) studied this question.
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