Anatomical variations in the posterior circulation of the circle of Willis affect collateral capacity during unilateral ICA stenosis, which may inform neurosurgical treatment strategies.
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Animal models show outlet-dependent collateral capacity with ICA stenosis; leaves open translation to human neurosurgical strategies.
The results demonstrate that different models have different collateral capacities in coping stenosis of unilateral ICA and these differences can be reflected by different outlets. The study could be used as a reference for neurosurgeon in choosing the best treatment strategy.
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Ren et al. (2015) studied this question.
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