What question did this study set out to answer?

To characterize tumor immune microenvironment infiltration patterns across human cancers and identify prognostic, immunotherapeutically relevant messenger RNA signatures in clear cell renal cell carcinoma.

November 17, 2016Genome biologyOpen Access

Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

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Authors

YŞYasin ŞenbabaoğluChan Zuckerberg Initiative (United States)RGRon S. GejmanColumbia University Irving Medical Center AWAndrew WinerSUNY Downstate Health Sciences University

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Implication

Genomic analysis reveals prognostic immune-related messenger RNA signatures in clear cell renal cell carcinoma, highlighting potential biomarkers for immunotherapy.

Key Points

To characterize tumor immune microenvironment infiltration patterns across human cancers and identify prognostic, immunotherapeutically relevant messenger RNA signatures in clear cell renal cell carcinoma.
Analyzed immune infiltration profiles across 19 distinct human cancer types.
Profiled messenger RNA expression patterns specifically in clear cell renal cell carcinoma datasets to identify biomarker signatures.
Identified distinct immune infiltration patterns across 19 human malignancies.
Uncovered specific messenger RNA signatures in clear cell renal cell carcinoma associated with patient prognosis and immunotherapy response potential.

Cite This Study

Şenbabaoğlu et al. (2016) studied this question.

synapsesocial.com/papers/69dbd1e27d378569a9836121 https://doi.org/10.1186/s13059-016-1092-z

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Implication

Genomic analysis reveals prognostic immune-related messenger RNA signatures in clear cell renal cell carcinoma, highlighting potential biomarkers for immunotherapy.

Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

Discussion

Member takes

Implication

Key Points

Cite This Study

Tumor immune microenvironment characterization in clear cell renal cell carcinoma identifies prognostic and immunotherapeutically relevant messenger RNA signatures

Discussion

Member takes

Implication

Key Points

Cite This Study

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