What question did this study set out to answer?

To establish a standardized multinational protocol assessing the distribution and patterns of lymph node metastases in esophageal carcinoma.

July 4, 2019BMC CancerOpen Access

Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: study protocol of a multinational observational study

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Authors

EHEliza HagensAmsterdam University Medical Centers MHMark I. van Berge HenegouwenApple (Israel)JSJohanna W. van SandickDutch Cancer Society

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Implication

Randomized trial reports a multinational protocol evaluating lymph node metastases in esophageal carcinoma, highlighting opportunities for targeted surgical staging.

Key Points

To establish a standardized multinational protocol assessing the distribution and patterns of lymph node metastases in esophageal carcinoma.
Multinational interventional trial protocol registered under clinical trial identifier NCT03222895 on July 19, 2017.
Defines standardized surgical mapping and pathological evaluation of lymphatic spread across anatomical nodal stations in esophageal cancer.
Clinical outcome metrics, event rates, and hazard ratios are pending formal trial execution and data collection as defined by the protocol.
The framework establishes uniform recording criteria to characterize primary lymphatic dissemination patterns quantitatively.

Cite This Study

Hagens et al. (2019) studied this question.

synapsesocial.com/papers/69dbd9723d9adb00e7685489 https://doi.org/10.1186/s12885-019-5761-7

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Implication

Randomized trial reports a multinational protocol evaluating lymph node metastases in esophageal carcinoma, highlighting opportunities for targeted surgical staging.

Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: study protocol of a multinational observational study

Discussion

Member takes

Implication

Key Points

Cite This Study

Distribution of lymph node metastases in esophageal carcinoma [TIGER study]: study protocol of a multinational observational study

Discussion

Member takes

Implication

Key Points

Cite This Study

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