What question did this study set out to answer?

To document the localization of lymphatic metastasis in thoracic esophageal squamous cell carcinoma and assess the survival impact of radical systematic lymph node dissection.

September 1, 1994Annals of SurgeryOpen Access

Radical Lymph Node Dissection for Cancer of the Thoracic Esophagus

View Full Paper

Ask AI

Bookmark

Authors

HAHiroshi AkiyamaNational Institute of Health Sciences MTMasahiko TsurumaruJuntendo University HUHarushi UdagawaOkinaka Memorial Adult Disease Research Institute

Discussion

Member takes

Implication

Cohort study reveals improved five-year survival with three-field lymph node dissection in thoracic esophageal cancer, suggesting extensive nodal clearance provides long-term curative benefits.

Key Points

To document the localization of lymphatic metastasis in thoracic esophageal squamous cell carcinoma and assess the survival impact of radical systematic lymph node dissection.
Retrospective analysis of 717 patients who underwent complete tumor resection (TNM R0) out of 1,298 patients treated between 1973 and 1993.
Compared survival outcomes between two-field thoracoabdominal dissection and extensive three-field collothoracoabdominal dissection.
Five-year survival for TNM R0 patients was 55.0% after three-field dissection compared to 38.3% after two-field dissection (log-rank p = 0.0013).
Survival advantages were particularly pronounced in stage III and IV disease attributable to nodal involvement.
Overall 5-year survival across all 913 resected patients was 42.4%.

Cite This Study

Akiyama et al. (1994) studied this question.

synapsesocial.com/papers/6a0cdc10df69d124d80262e2 https://doi.org/10.1097/00000658-199409000-00012

View Full Paper

Ask AI

Bookmark

Implication

Cohort study reveals improved five-year survival with three-field lymph node dissection in thoracic esophageal cancer, suggesting extensive nodal clearance provides long-term curative benefits.

Radical Lymph Node Dissection for Cancer of the Thoracic Esophagus

Discussion

Member takes

Implication

Key Points

Cite This Study

Radical Lymph Node Dissection for Cancer of the Thoracic Esophagus

Discussion

Member takes

Implication

Key Points

Cite This Study

Also Consider

Also Consider