May 21, 2015Open Access

89Zr-Labeled Versus 124I-Labeled αHER2 Fab with Optimized Plasma Half-Life for High-Contrast Tumor Imaging In Vivo

CMClaudia T. MendlerKlinikum rechts der Isar TGTorben GehringKlinikum rechts der Isar HWHans‐Jürgen WesterTheranostics (New Zealand)

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Abstract

Both (89)Zr- and (124)I-labeled versions of αHER2 Fab-PAS200 allowed PET tumor imaging with high contrast. With its residualizing radiometal, the tracer (89)Zr⋅Df-Fab-PAS200 showed better in vivo stability and higher tumor uptake.

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Mendler et al. (Thu,) studied this question.

synapsesocial.com/papers/69dbdbf77d378569a9836627 https://doi.org/https://doi.org/10.2967/jnumed.114.149690

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