Why the study?
Does positive-pressure proportional assist ventilation prevent exercise-induced diaphragmatic fatigue in subjects undergoing heavy exercise?
Population
Subjects performing heavy-intensity whole body exercise to exhaustion at 80-85% maximal oxygen consumption
Comparison
Positive-pressure proportional assist… vs Control conditions (exercise without PAV)
Design
Other
Follow-up
Up to 60 minutes postexercise
Authors
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May warrant caution in clinical translation from healthy subjects; leaves open patient trials for respiratory muscle unloading.
Does positive-pressure proportional assist ventilation prevent exercise-induced diaphragmatic fatigue in subjects undergoing heavy exercise?
Unloading respiratory muscles with proportional assist ventilation during heavy exercise prevents exercise-induced diaphragmatic fatigue, demonstrating that respiratory muscle workload is a critical determinant of this fatigue.
Babcock et al. (2002) studied this question.
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