Why the study?
Does off-pump CABG reduce the composite outcome of death, stroke, myocardial infarction, repeat revascularization, or new renal-replacement therapy compared to on-pump CABG in patients 75 years of age or older?
Does off-pump CABG reduce the composite outcome of death, stroke, myocardial infarction, repeat revascularization, or new renal-replacement therapy compared to on-pump CABG in patients 75 years of age or older?
In elderly patients (≥75 years), off-pump CABG does not significantly reduce the composite of death, stroke, MI, repeat revascularization, or new renal-replacement therapy compared to on-pump CABG at up to 12 months.
Either technique acceptable in patients ≥75 years; extends neutral RCT findings to older adults.
In patients 75 years of age or older, there was no significant difference between on-pump and off-pump CABG with regard to the composite outcome of death, stroke, myocardial infarction, repeat revascularization, or new renal-replacement therapy within 30 days and within 12 months after surgery. (Funded by Maquet; GOPCABE ClinicalTrials.gov number, NCT00719667.).
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Diegeler et al. (2013) studied this question.
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