Why the study?
Does off-pump coronary artery bypass surgery reduce stroke compared to on-pump coronary artery bypass surgery?
Does off-pump coronary artery bypass surgery reduce stroke compared to on-pump coronary artery bypass surgery?
Off-pump coronary artery bypass surgery appears to reduce the risk of stroke compared to on-pump surgery based on an updated meta-analysis of randomized trials.
OPCAB may lower stroke risk versus ONCAB in CABG; reinforces RCT evidence independent of population differences.
Our meta-analysis incorporating recent trials suggests that there appears to be a beneficial effect of OPCAB on stroke. Moreover, our meta-regression does not support the hypothesis that differences in study populations are responsible for the observed outcomes, although pooled individual patient-data would be better suited to confirm these findings.
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Afilalo et al. (2011) studied this question.
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