Why the study?
Do acute changes in arterial carbon dioxide affect diaphragmatic contractility and endurance in normal men?
Population
4 normal men
Comparison
Acute changes in partial pressure of arterial… vs Normocapnia
Design
Other
Authors
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Acute hypercapnia may impair diaphragmatic endurance in ventilated patients; leaves open effects on weaning outcomes in respiratory failure.
Do acute changes in arterial carbon dioxide affect diaphragmatic contractility and endurance in normal men?
Acute respiratory acidosis equivalent to an arterial carbon dioxide tension of about 54 mm Hg decreases the contractility and endurance time of the diaphragm in human beings.
Juan et al. (1984) studied this question.
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