Myocardial triglyceride accumulation in moderate obesity correlates with free fatty acid exposure and peripheral vascular resistance, occurring prior to the development of left ventricular hypertrophy.
Supports myocardial triglyceride preceding LV hypertrophy in moderate obesity; leaves open causal role and therapeutic implications.
The accumulation of triglyceride in and around the myocardium of moderately obese individuals is significant, and it is related to FFA exposure, generalized ectopic fat excess, and peripheral vascular resistance. These changes precede LV overload and hypertrophy.
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Kankaanpää et al. (2006) studied this question.
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