Why the study?
Does exercise training during childhood and adolescence improve LV diastolic function later in life in individuals with HCM or an HCM-causative genotype?
Does exercise training during childhood and adolescence improve LV diastolic function later in life in individuals with HCM or an HCM-causative genotype?
Exercise training during childhood and adolescence is associated with better long-term LV diastolic function in patients with or genetically predisposed to hypertrophic cardiomyopathy.
Early exercise may benefit diastolic function in HCM; hypothesis-generating and should not yet change practice.
More exercise training during childhood and adolescence was associated with favorable LV diastolic function in both HCM LVH+ and G+ LVH- groups, regardless of presence of hypertrophy at the time of examination. These results indicate that exercise training initiated during childhood and adolescence has positive effects on cardiac function later in life for individuals with HCM or an HCM-causative genotype.
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Andreassen et al. (2022) studied this question.
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