Population
Individual titin molecules and recombinant titin immunoglobulin segments
Design
Preclinical
Authors
Loading...
Titin Ig domains show reversible force-dependent unfolding; extends sarcomere mechanobiology models but leaves open cardiac disease relevance.
Single-molecule AFM demonstrates that individual titin immunoglobulin domains undergo reversible unfolding when subjected to mechanical force.
Rief et al. (1997) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: