Canadian Urological Association guideline: Muscle-invasive bladder cancer

On average, an estimated 9000 incident cases of bladder cancer are diagnosed in Canada annually.1 Of these, approximately 25% will be muscle-invasive at presentation. Muscle-invasive bladder cancer (MIBC) possesses an aggressive biology that portends metastatic disease. Overall, the five-year mortality of patients diagnosed with localized MIBC is approximately 40–50%.2,3 In the setting of metastatic disease, long-term survival is rare. To help streamline treatment and optimize care, the Canadian Urological Association (CUA) commissioned the creation of a national guideline on MIBC.