April 3, 2002Open Access

Osteopontin Identified as Lead Marker of Colon Cancer Progression, Using Pooled Sample Expression Profiling

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Abstract

Sample pooling can be a powerful, cost-effective, and rapid means of identifying the most common changes in a gene expression profile. We identified osteopontin as a clinically useful marker of tumor progression by use of gene expression profiling on pooled samples.

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Deepak Agrawal (Wed,) studied this question.

synapsesocial.com/papers/69dc32dc719b3a2c2d2744dd https://doi.org/https://doi.org/10.1093/jnci/94.7.513

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1An Evaluation of the Carcinoembryonic Antigen (CEA) Test for Monitoring Patients With Resected Colon Cancer1993 · 440 citations
2Elevated expression of secreted phosphoprotein I (osteopontin, 2ar) as a consequence of neoplastic transformation.1990 · 204 citations
3Molecular and cellular basis of genetic resistance to bacterial infection: the role of the early T-lymphocyte activation-1/osteopontin gene.1993 · 202 citations
4The role of tissue microdissection in cancer research.2001 · 51 citations
5Cluster analysis and display of genome-wide expression patterns1998 · 16,401 citations

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