Clinical study shows accelerated lung function loss after exacerbations in high-eosinophil COPD patients without steroid therapy, suggesting targeted corticosteroid treatment prevents respiratory...
Exacerbations are associated with a more rapid loss of lung function among COPD patients with elevated blood eosinophils, defined as ≥350 cells/µL, not treated with ICS. More aggressive prevention of exacerbations using ICS in such patients may prevent excess loss of lung function.
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Kerkhof et al. (2020) studied this question.
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