Observational study reveals favorable seizure outcomes after resective surgery in complex epilepsy, indicating distinct causes for early and late postoperative recurrences.
Key Points
To assess long-term seizure outcomes following resective surgery in patients with complex epilepsy evaluated using invasive intracranial EEG, and to characterize factors driving early versus late seizure recurrence.
Evaluation of patients with medically refractory, complex epilepsy who underwent invasive intracranial electroencephalography (EEG) monitoring followed by surgical resection.
Resective surgery achieves favorable long-term seizure control in patients with complex epilepsy requiring invasive electrode investigations.
Early postoperative seizure recurrences typically stem from mislocalization or incomplete resection of the epileptogenic zone, whereas late relapses are driven by subsequent epileptogenesis.