Population
In vitro biochemical assays using recombinant human Scar protein, Arp2/3 complex, and actin
Comparison
Full-length and N-terminally truncated… vs Arp2/3 complex alone or actin alone
Design
Preclinical
Authors
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No immediate clinical implications in cardiovascular care; leaves open Scar-Arp2/3 roles in human disease models.
Scar and related proteins (WASp, N-WASp) act as endogenous activators of actin polymerization by the Arp2/3 complex.
Machesky et al. (1999) studied this question.
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