Shows melatonin protects cardiac microvascular endothelial cells from ischemia-reperfusion injury by suppressing autophagy via AMPK/mTOR signaling, highlighting potential cardioprotective benefits.
Melatonin played an important and protective role in CMECs by inhibiting autophagy against IRI via the AMPK/mTOR system.
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Chen et al. (2018) studied this question.
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