Decreasing in-hospital systolic blood pressure was associated with a 19% lower risk of heart failure hospitalization or all-cause mortality (HR 0.81) compared to stable normal/low blood pressure.
Cohort (n=1,490)
Yes
Does an in-hospital decline in systolic blood pressure improve outcomes in acute heart failure patients with elevated admission systolic blood pressure?
In patients hospitalized for acute heart failure with elevated admission blood pressure, an in-hospital decline in systolic blood pressure is associated with better clinical outcomes.
Effect estimate: HR 0.81 (95% CI 0.66-0.99)
Absolute Event Rate: 36.4% vs 42.9%
p-value: p=0.040
In this real-world, multinational cohort of 1490 acute heart failure patients, in-hospital decline in systolic blood pressure was independently associated with improved outcomes in those with an elevated systolic blood pressure at admission.
Carminati et al. (Thu,) conducted a cohort in Acute heart failure (n=1,490). Decreasing systolic blood pressure trajectory vs. Stable normal/low systolic blood pressure trajectory was evaluated on Composite of first heart failure hospitalisation or all-cause mortality (HR 0.81, 95% CI 0.66-0.99, p=0.040). Decreasing in-hospital systolic blood pressure was associated with a 19% lower risk of heart failure hospitalization or all-cause mortality (HR 0.81) compared to stable normal/low blood pressure.