Patients with urinary urgency had higher GSS compared to controls without urgency. Cases with higher GSS scores had more severe OAB symptoms and worse HRQL. These findings suggest a subset of urinary urgency patients may exhibit global, multisystem hypersensitivity to sensory input. In these individuals, bladder symptoms may represent a manifestation of broader sensory dysregulation rather than an isolated organ-specific pathology.
Lai et al. (Fri,) studied this question.