Phenotyping study reveals sensory hypersensitivity in urinary urgency cases, suggesting broader symptoms.
Patients with urinary urgency had higher GSS compared to controls without urgency. Cases with higher GSS scores had more severe OAB symptoms and worse HRQL. These findings suggest a subset of urinary urgency patients may exhibit global, multisystem hypersensitivity to sensory input. In these individuals, bladder symptoms may represent a manifestation of broader sensory dysregulation rather than an isolated organ-specific pathology.
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Lai et al. (2026) studied this question.
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