Clinical and 18F-FDG PET/CT Imaging Characteristics of Post-radiotherapy Sacral Insufficiency Fractures in Cervical Cancer Patients

Wanling Qi; Fengxiang Liao; Zhehuang Luo; Mingyan Shao

doi:10.2174/0115734056428627260223054010

April 8, 2026Current Medical Imaging Formerly Current Medical Imaging ReviewsOpen Access

Clinical and 18F-FDG PET/CT Imaging Characteristics of Post-radiotherapy Sacral Insufficiency Fractures in Cervical Cancer Patients

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Key Points

This study aims to define the qualitative and quantitative imaging characteristics of sacral insufficiency fractures in cervical cancer patients post-radiotherapy.
Retrospective analysis of 32 cervical cancer patients with post-radiotherapy sacral insufficiency fractures
Evaluation of qualitative (fracture patterns, FDG uptake morphology) and quantitative (SUVmax, SUR-BP ratio, CT densitometry) parameters via 18F-FDG PET/CT
Comparison of imaging findings with clinical follow-up data
SIFs predominantly occurred in postmenopausal women (93.7%) at a median of 14 months post-radiotherapy
Characteristic imaging findings included linear or curvilinear hypoattenuating fracture lines in 68.7% of patients
On PET/CT, a diffuse/patchy FDG uptake pattern was seen in 96.8% of patients with low metabolic activity (mean SUVmax 2.45)

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Implication

Retrospective analysis reveals 18F-FDG PET/CT imaging characteristics of sacral fractures in cervical cancer patients, suggesting key diagnostic features for differentiation from metastases.

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Cite This Study

Qi et al. (2026) studied this question.

synapsesocial.com/papers/69dc88303afacbeac03ea18d https://doi.org/10.2174/0115734056428627260223054010

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Clinical and 18F-FDG PET/CT Imaging Characteristics of Post-radiotherapy Sacral Insufficiency Fractures in Cervical Cancer Patients

Key Points

No abstract yet

Implication

Discussion

Cite This Study

Clinical and 18F-FDG PET/CT Imaging Characteristics of Post-radiotherapy Sacral Insufficiency Fractures in Cervical Cancer Patients

Key Points

No abstract yet

Implication

Discussion

Cite This Study

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