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April 7, 2026

Diagnostic test accuracy of the pattern electroretinogram for glaucoma: a systematic review and meta-analysis.

Tian Cheng Taikang Yao Di Zhang Jianhua Zhang Lingge Suo

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Key Points

This research aims to evaluate the diagnostic accuracy of the pattern electroretinogram (PERG) for detecting glaucoma, particularly in its early stages.
Conducted a systematic review of existing literature on PERG and glaucoma diagnosis
Performed a meta-analysis to assess the diagnostic test accuracy and performance metrics
Analyzed the effects of protocol optimization, including Hemifield stimulation, on detection sensitivity
Current literature affirms the clinical viability of PERG for glaucoma detection
Inconsistent performance metrics were observed in the preperimetric phase
Optimized stimulation protocols might improve sensitivity for early functional loss detection

Implication

A systematic review finds the pattern electroretinogram shows promise for early glaucoma detection, suggesting optimization is needed.

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Cite This Study

Cheng et al. (2026) studied this question.

synapsesocial.com/papers/69dc88303afacbeac03ea240 https://doi.org/10.1016/j.jcjo.2026.03.018

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