A systematic review finds the pattern electroretinogram shows promise for early glaucoma detection, suggesting optimization is needed.
Current literature affirms the clinical viability of PERG; however, inconsistent performance metrics in the preperimetric phase suggest that standard full-field configurations may lack the requisite sensitivity to capture incipient localized damage. Preliminary findings suggest that protocol optimization-potentially involving Hemifield stimulation-may offer advantages for detecting early functional loss, warranting further validation in future studies.
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Cheng et al. (2026) studied this question.
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