Gaps in Guideline Adherence for Primary Sclerosing Cholangitis in North America—A 5‐Year Analysis

Adrielly Martins; A. Nagarjuna Reddy; Richard Dean; Stuart C. Gordon; Daniel Pratt; Michael Li; Lisa Forman; Craig Lammert; Kidist Yiman; Juan F. Gallegos‐Orozco; Elizabeth J. Carey; Alan Bonder; Barry Schlansky; Aldo J. Montaño‐Loza; Ellina Lytvyak; David S. Goldberg; Scott Naugler; Lei Yu; David N. Assis; Christopher L. Bowlus; Cynthia Levy

doi:10.1111/liv.70645

Key Points

To analyze adherence to care guidelines for primary sclerosing cholangitis (PSC) in North America over five years.
Analyzed guideline adherence data for PSC care over the past five years.
Identified specific practices where adherence was low, such as colonoscopy and cancer imaging.
Examined differences in guideline recommendations among various medical societies.
Observed suboptimal adherence to guidelines for colonoscopy and colorectal cancer surveillance in PSC-IBD.
Noted variability in adherence for newer and evolving guideline practices like fibrosis assessment.
Highlighted the need for standardized care and addressing socioeconomic barriers to improve PSC outcomes.

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Implication

Analysis reveals low guideline adherence for PSC care in North America, indicating a need for improved standards.

Abstract

Adherence to guideline-based care in PSC remains suboptimal in North America Suboptimal adherence was observed for strongly recommended practices with longstanding guideline support (colonoscopy to establish IBD status; annual CRC surveillance in PSC-IBD) as well as practices where guideline consensus has evolved more recently or where societies differ (baseline fibrosis assessment; hepatobiliary cancer imaging). Efforts to standardise care and address socioeconomic barriers are urgently needed to improve outcomes.

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Cite This Study

Martins et al. (2026) studied this question.

synapsesocial.com/papers/69dc887f3afacbeac03ea51a https://doi.org/10.1111/liv.70645

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Gaps in Guideline Adherence for Primary Sclerosing Cholangitis in North America—A 5‐Year Analysis

Key Points

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Implication

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Discussion

Cite This Study

Gaps in Guideline Adherence for Primary Sclerosing Cholangitis in North America—A 5‐Year Analysis

Key Points

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

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