Systematic review evaluates the link between antihypertensive drugs and dementia incidence in older adults, highlighting the need for precision in treatment.
Current evidence is limited by few studies and short follow-up; large-scale randomized controlled trials with dementia as a primary endpoint, head-to-head drug class comparisons, and inclusion of long-term care residents-who bear the highest disease burden yet are underrepresented in trials-are urgently needed to inform precision prescribing guidelines.
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Ding et al. (2026) studied this question.
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