Application of luminescence-producing Mycobacterium tuberculosis strains for evaluating anti-tuberculosis drug and vaccine efficacy in vitro and in vivo
Evaluates drug and vaccine efficacy in a TB model using bioluminescent Mycobacterium tuberculosis strains, suggesting a new imaging method for faster testing.
Key Points
To develop and utilize bioluminescent strains of Mycobacterium tuberculosis for real-time monitoring of infection and drug/vaccine efficacy.