Why the study?
Primary pericardial mesothelioma is associated with high mortality, late presentation, and diagnostic uncertainty, making awareness of this rare malignant entity in unusual cardiac presentations important.
Primary pericardial mesothelioma should be considered in the differential diagnosis of effusive constrictive pericarditis, especially when there is no clear explanation or response to treatment.
Raises suspicion for rare malignancy in refractory cases; hypothesis-generating from single case report.
Constrictive pericarditis is an uncommon presentation of PPM. Due to the high mortality rate and late presentation, difficulties and uncertainties in diagnosis, being aware of this rare malignant entity in different cardiac manifestations, particularly when there is no clear explanation or response to treatment in such conditions, is highly important.
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Savarrakhsh et al. (2021) studied this question.
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