Why the study?
Does pulmonary artery denervation with an intravascular ultrasound catheter improve hemodynamics and functional capacity in patients with PAH on background dual or triple therapy?
Does pulmonary artery denervation with an intravascular ultrasound catheter improve hemodynamics and functional capacity in patients with PAH on background dual or triple therapy?
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Intravascular ultrasound pulmonary artery denervation appears safe and is associated with improved hemodynamics and functional capacity in patients with PAH on background medical therapy.
In this multicenter early feasibility study, PDN with an intravascular ultrasound catheter was performed without procedure-related adverse events and was associated with a reduction in PVR and increases in 6-min walk distance and daily activity in patients with PAH on background dual or triple therapy.
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Rothman et al. (2020) studied this question.
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