Demonstrates a direct relationship between pulmonary arterial pulse pressure and the activity of afferent pulmonary vascular fibres in an animal model.
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Animal data link pulmonary vascular fibre activity to pulse pressure; human relevance and therapeutic implications remain untested.
A method of recording pulmonary arterial pressure in animals with closed chests and spontaneous respiration is described. 2. The activity of pulmonary vascular fibres is shown to bear a direct relationship to the pulmonary arterial pulse pressure. Some evidence is put forward for the belief that the receptors of these fibres are situated on the arterial side of the pulmonary vascular bed.
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Pearce et al. (1951) studied this question.
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