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April 12, 2021Journal of Clinical Medicine82 citationsOpen Access

Enhanced Recovery after Surgery: History, Key Advancements and Developments in Transplant Surgery

HGHenry John GolderVPVassilios Papalois

Structured PICO

Does the implementation of Enhanced Recovery after Surgery (ERAS) protocols improve outcomes such as length of stay and costs in surgical and transplant patients?

P
Population
Surgical patients, with a focus on transplant surgery (liver and kidney transplantation)
I
Intervention
Enhanced recovery after surgery (ERAS) protocols (including carbohydrate loading, bowel preparation, patient education, goal-directed fluid therapy, early mobilisation, and enteral nutrition)
O
Outcome
Length of hospital stay and healthcare costs

ERAS protocols significantly reduce length of hospital stay and healthcare costs across surgical specialties, though uptake and literature in transplant surgery remain limited.

Limitations

  • Scarcity of literature in the transplantation field

Abstract

Enhanced recovery after surgery (ERAS) aims to improve patient outcomes by controlling specific aspects of perioperative care. The concept was introduced in 1997 by Henrik Kehlet, who suggested that while minor changes in perioperative practise have no significant impact alone, incorporating multiple changes could drastically improve outcomes. Since 1997, significant advancements have been made through the foundation of the ERAS Society, responsible for creating consensus guidelines on the implementation of enhanced recovery pathways. ERAS reduces length of stay by an average of 2. 35 days and healthcare costs by 639. 06 per patient, as identified in a 2020 meta-analysis of ERAS across multiple surgical subspecialties. Carbohydrate loading, bowel preparation and patient education in the pre-operative phase, goal-directed fluid therapy in the intra-operative phase, and early mobilisation and enteral nutrition in the post-operative phase are some of the interventions that are commonly implemented in ERAS protocols. While many specialties have been quick to incorporate ERAS, uptake has been slow in the transplantation field, leading to a scarcity of literature. Recent studies reported a 47% reduction in length of hospital stay (LOS) in liver transplantation patients treated with ERAS, while progress in kidney transplantation focuses on pain management and its incorporation into enhanced recovery protocols.

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Cite This Study

Golder et al. (2021) studied this question.

synapsesocial.com/papers/69dcba937873f5f05b1339a8https://doi.org/10.3390/jcm10081634
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Patterns in current perioperative practice: survey of colorectal surgeons in five northern European countries2005 · 258 citations
  2. 2Enhanced Recovery After Surgery2019 · 850 citations
  3. 3The History of Enhanced Recovery After Surgery and the ERAS Society2017 · 139 citations
  4. 4The Impact of Enhanced Recovery Protocol Compliance on Elective Colorectal Cancer Resection2015 · 629 citations
  5. 5Adherence to the Enhanced Recovery After Surgery Protocol and Outcomes After Colorectal Cancer Surgery2011 · 949 citations