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March 6, 2023Frontiers in EndocrinologyOpen Access

Involvement of p38 MAPK in Leydig cell aging and age-related decline in testosterone

Dandan Luo Xiangyu Qi Xiaoqin Xu Leilei Yang Chunxiao Yu Qingbo Guan

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Abstract

Our study suggested that obesity was an important risk factor for Leydig cell aging. p38 MAPK was involved in Leydig cell aging induced by age and obesity. The inhibition of p38 MAPK could delay Leydig cell aging and alleviate decline in testosterone.

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Cite This Study

Luo et al. (2023) studied this question.

synapsesocial.com/papers/69dcc1c2c099bcfdbb1334bd https://doi.org/10.3389/fendo.2023.1088249

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