Does moderate therapeutic hypothermia at 33°C for 24 hours improve survival with a favorable neurologic outcome at day 90 in patients with coma resuscitated from cardiac arrest with nonshockable rhythm?
Moderate therapeutic hypothermia at 33°C for 24 hours improves 90-day survival with favorable neurologic outcome in comatose patients resuscitated from nonshockable cardiac arrest.
Among patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm, moderate therapeutic hypothermia at 33°C for 24 hours led to a higher percentage of patients who survived with a favorable neurologic outcome at day 90 than was observed with targeted normothermia. (Funded by the French Ministry of Health and others; HYPERION ClinicalTrials.gov number, NCT01994772.).
Lascarrou et al. (Wed,) studied this question.