Why the study?
Does moderate therapeutic hypothermia at 33°C for 24 hours improve survival with a favorable neurologic outcome at day 90 in patients with coma resuscitated from cardiac arrest with nonshockable rhythm?
Does moderate therapeutic hypothermia at 33°C for 24 hours improve survival with a favorable neurologic outcome at day 90 in patients with coma resuscitated from cardiac arrest with nonshockable rhythm?
Moderate therapeutic hypothermia at 33°C for 24 hours improves 90-day survival with favorable neurologic outcome in comatose patients resuscitated from nonshockable cardiac arrest.
Supports moderate hypothermia at 33°C for 24 h in comatose nonshockable arrest survivors; extends RCT evidence to this high-risk population.
Among patients with coma who had been resuscitated from cardiac arrest with nonshockable rhythm, moderate therapeutic hypothermia at 33°C for 24 hours led to a higher percentage of patients who survived with a favorable neurologic outcome at day 90 than was observed with targeted normothermia. (Funded by the French Ministry of Health and others; HYPERION ClinicalTrials.gov number, NCT01994772.).
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Lascarrou et al. (2019) studied this question.
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