DNA in command: An enantioselective Diels–Alder reaction can be achieved using human telomeric G-quadruplex DNA-based catalysts. The absolute configuration of the product can be reversed when the conformation of G-quadruplex DNA is switched from antiparallel to parallel, and both the reaction rate and the enantioselectivity of the Diels–Alder reaction were found to be dependent on the DNA sequence.
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Wang et al. (2012) studied this question.
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