Elevated cardiac biomarkers in CKD patients usually indicate true underlying cardiovascular disease rather than just decreased renal clearance, remaining useful for diagnosis and prognosis.
CKD is common and associated with acceleration of cardiovascular disease. Cardiac biomarker concentrations are often increased even in an absence of symptoms; typically reflecting the extent of underlying cardiovascular disease rather than impairment of renal clearance. Thoughtful interpretation of cardiac biomarkers in those with CKD can continue to provide important diagnostic and prognostic information.
deFilippi et al. (Fri,) studied this question.