Pharmacological activation of NPR-C may represent an innovative approach to treating peripheral artery disease and ischemic cardiovascular disorders by promoting angiogenesis and vascular remodeling.
These data define a central (patho)physiological role for CNP in angiogenesis and vascular remodeling in response to ischemia and provide the rationale for pharmacological activation of NPR-C as an innovative approach to treating peripheral artery disease and ischemic cardiovascular disorders.
Bubb et al. (Thu,) studied this question.
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