Expression of Endothelin-1 in the Lungs of Patients with Pulmonary Hypertension
Population
Patients with pulmonary hypertension
Design
Other
Authors
Discussion
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Member takes
Implication
Endothelin-1 merits mechanistic study in pulmonary hypertension; this Level 5 association leaves causal and therapeutic roles open.
Structured PICO
P
Population
Patients with pulmonary hypertension
O
Outcome
Expression of endothelin-1 in vascular endothelial cellssurrogate
Increased local production of endothelin-1 in vascular endothelial cells may contribute to the vascular abnormalities associated with pulmonary hypertension.
Cite This Study
Giaid et al. (1993) studied this question.