Why the study?
Does the degree of coronary microvascular dysfunction predict clinical deterioration and death in patients with hypertrophic cardiomyopathy?
Does the degree of coronary microvascular dysfunction predict clinical deterioration and death in patients with hypertrophic cardiomyopathy?
Severe microvascular dysfunction is a strong independent predictor of adverse outcomes in hypertrophic cardiomyopathy, identifying high-risk patients even before symptom onset.
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May aid pre-symptomatic risk stratification in HCM; leaves open whether targeting microvascular dysfunction improves outcomes.
Cecchi et al. (2003) studied this question.
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