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April 5, 2004Proceedings of the Royal Society B Biological SciencesOpen Access

Two steps forward, one step back: the pleiotropic effects of favoured alleles

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SOSarah P. OttoUniversity of British Columbia

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Sarah P. Otto (2004) studied this question.

synapsesocial.com/papers/69dcf7aae3a90a2e2f1335cbhttps://doi.org/10.1098/rspb.2003.2635
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Also Consider

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  1. 1The Genetics of Adaptation: The Roles of Pleiotropy, Stabilizing Selection and Drift in Shaping the Distribution of Bidirectional Fixed Mutational Effects2003 · 50 citations
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  3. 3A Mathematical Theory of Natural and Artificial Selection, Part V: Selection and Mutation1927 · 1,432 citations
  4. 4Deleterious mutations, apparent stabilizing selection and the maintenance of quantitative variation.1992 · 129 citations