Do direct oral anticoagulants prevent VTE as effectively as low-molecular-weight heparin for post-operative thromboprophylaxis in patients undergoing cancer-related surgeries?
DOACs are a viable, non-inferior alternative to LMWH for post-operative thromboprophylaxis in cancer surgeries, with potential superiority in urological procedures.
DOACs appear non-inferior to LMWH for post-operative thromboprophylaxis in patients undergoing cancer-related surgeries, with comparable safety. The superior VTE prevention in urological cancer surgeries and Apixaban's favorable safety profile warrant further investigation. Moreover, additional research is necessary to clarify the roles of specific DOACs and optimal prophylaxis strategies across various cancer types and surgical procedures.
Mousavi et al. (Thu,) studied this question.