Abstract 17 O‐NMR spectroscopy has found limited application as a structural probe due to the experimental problems associated with a quadrupolar nucleus having low natural abundance. A survey of data obtained from systematic studies of structurally related compounds shows, however, that large chemical shift differences are usually obtained for structurally nonequivalent nuclei, and that characteristic chemical shift values are observed for specific chemical environments. The present day availability of 17 O enriched materials and Fourier transform NMR instrumentation should allow extensive application of the 17 O‐NMR technique to structural problems in the immediate future.
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W. G. Klemperer (1978) studied this question.
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