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June 4, 2003Circulation

Comparison of the Short-Term Survival Benefit Associated With Revascularization Compared With Medical Therapy in Patients With No Prior Coronary Artery Disease Undergoing Stress Myocardial Perfusion Single Photon Emission Computed Tomography

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Why the study?

Does revascularization improve short-term survival compared to medical therapy in patients with no prior coronary artery disease and moderate to large inducible ischemia on SPECT?

Population

Patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission…

Comparison

Revascularization vs Medical therapy

Design

Cohort

Follow-up

Short-term

Authors

RHRory HachamovitchCardiac ImagingSHSean W. HayesCedars-Sinai Medical CenterJFJohn D. FriedmanCardiac Imaging

Discussion

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Implication

May support revascularization in moderate-large ischemia on SPECT; leaves open randomized confirmation of short-term survival benefit without prior CAD.

Structured PICO

Does revascularization improve short-term survival compared to medical therapy in patients with no prior coronary artery disease and moderate to large inducible ischemia on SPECT?

P
Population
Patients with no prior coronary artery disease undergoing stress myocardial perfusion single photon emission computed tomography (SPECT) who have moderate to large amounts of inducible ischemia
I
Intervention
Revascularization
C
Comparator
Medical therapy
O
Outcome
Short-term survivalhard clinical

Revascularization may offer a short-term survival benefit over medical therapy in patients without prior CAD who demonstrate moderate to large amounts of inducible ischemia on SPECT.

Limitations

  • Requires confirmation by prospective evaluations

Cite This Study

Hachamovitch et al. (2003) studied this question.

synapsesocial.com/papers/69dd1ef63ffc04feac1334c8https://doi.org/10.1161/01.cir.0000072790.23090.41
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Also Consider

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  1. 1Continuing evolution of therapy for coronary artery disease. Initial results from the era of coronary angioplasty.1994 · 423 citations
  2. 2The Effectiveness of Right Heart Catheterization in the Initial Care of Critically III Patients1996 · 2,237 citations
  3. 3The central role of the propensity score in observational studies for causal effects1983 · 31,584 citations
  4. 4The Evolution of Medical and Surgical Therapy for Coronary Artery Disease1989 · 301 citations