Melasma Management: A Comprehensive Review of Treatment Strategies Including BTX‐A

Melasma is a challenging dermatologic condition due to its chronicity and various intrinsic and extrinsic factors that influence its pathogenesis. While current treatment options for melasma include topical, oral, and light-based therapies, recent studies suggest that BTX-A may hold potential as a viable treatment modality for melasma. Despite the mechanism of action remaining unclear, it is hypothesized that BTX-A inhibition of Ach receptors on melanocytes could play a role in the reduction of melanogenesis. BTX-A treatment in melasma-affected skin demonstrates statistically significant reduction in hyperpigmented lesions associated with melasma.