The results suggest a close association between MMP-2/TIMP-2 expression and local tumor invasion, with a disruption in expression of the two genes leading to disease progression. Future studies should focus on the activity of these enzymes and on the ratio of enzyme/inhibitor expression, which may become a useful prognostic marker in prostate cancer.
No takes yet. Share an insight, caveat, or question.
Still et al. (2000) studied this question.
Synapse has enriched one closely related paper. Consider it for comparative context: